391: What Can Chronic Uncertainty Teach Us About Control, Acceptance, and Resilience?
Guest
Jonathan Gluck is a writer and editor whose work has appeared in The New York Times and The Washington Post. He was deputy editor of New York magazine for ten years, after which he worked as managing editor of Vogue. He currently works at Fast Company. His work has been recognized with multiple National Magazine Awards. He is the author of An Exercise in Uncertainty, a memoir of how his journey with incurable cancer has reshaped his identity, marriage, and daily life.
Summary
In this deeply candid conversation, Jon recounts his 22-year journey living with multiple myeloma, an incurable but treatable bone-marrow cancer. He describes the shock of his diagnosis at age 38 and the long, winding road of tests, remissions, relapses, and emerging treatments that have kept him alive. The discussion explores how Gluck navigates profound uncertainty, the illusion of control, and the emotional toll that chronic illness places not only on the patient but also on family and relationships. He and his wife confronted the strain of living in medical limbo, ultimately turning to therapy to rebuild connection during what he calls becoming “cancer zombies.”
The conversation also highlights the restorative role of fly fishing, which Gluck describes as one of the few activities capable of placing him entirely in the present. This genuine flow state quiets fear and anxiety. He shares broader lessons about empathy, how to speak to someone with a serious diagnosis, and the importance of intentionally pursuing joy, connection, and meaning while living alongside uncertainty.
The Essential Point
The heart of the discussion is Jon’s insight into living meaningfully in the face of uncertainty. His story shows that while we cannot control the inevitabilities of illness or life’s unpredictability, we can control how we show up—seeking information, accepting our limits, nurturing relationships, and embracing activities that restore us. His emphasis on intentionally choosing joy, connection, and presence—even in the shadow of chronic illness—offers a universal lesson for anyone facing their own uncertainties.
Social Media
Facebook
https://www.facebook.com/jon.gluck.3
https://www.linkedin.com/in/jonathan-gluck-b32b6898/
About Jeff
Jeff Ikler is the Director of Quetico Leadership and Career Coaching. “Quetico” (KWEH-teh-co). He works with leaders in all aspects of life to identify and overcome obstacles in their desired future. He came to the field of coaching after a 35-year career in educational publishing. Prior to his career in educational publishing, Jeff taught high school U.S. history and government.
Jeff has hosted the “Getting Unstuck—Cultivating Curiosity” podcast for 5 years. The guests and topics he explores are designed to help listeners think differently about the familiar and welcome the new as something to consider. He is also the co-host of the Cultivating Resilience – A Whole Community Approach to Alleviating Trauma in Schools, which promotes mental health and overall wellness.
Jeff co-authored Shifting: How School Leaders Can Create a Culture of Change. Shifting integrates leadership development and change mechanics in a three-part change framework to help guide school leaders and their teams toward productive change.
Show Credits
"Getting Unstuck" is commercial-free. It’s brought to you by Jeff Ikler, his amazing guests, and Neil Hughes, the best engineer a podcaster could ask for.
"Getting Unstuck" theme music: Original composition of "Allegro ben ritmato e deciso" by George Gershwin. Arrangement and recording courtesy of Bruno Lecoeur.


